A New Prenylated Flavanone from Derris trifoliata Lour.
نویسندگان
چکیده
منابع مشابه
A new prenylated flavanone from Derris trifoliata Lour.
A new flavanone, 4',5,7-trihydroxy-6,8-di-(2-hydroxy-3-methylbut-3-enyl)- flavanone, was isolated from the aerial parts of Derris trifoliate, together with eleven known compounds: rotenone, tephrosin, 12a-hydroxyrotenone, deguelin, 6a,12a-dehydro-rotenone, dehydrodeguelin, 7a-O-methyldeguelol, 7a-O-methylelliptonol, 5,7,3',4'-tetra-hydroxy-6,8-diprenylisoflavone, daidzein and 4'-hydroxy-7-metho...
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From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new flavanone derivative (S)-lupinifolin 4 -́methyl ether was isolated. In addition, the known flavonoids lupinifolin and rotenone were identified. The structures were determined on the basis of spectroscopic evidence. Lupinfolin showed moderate in vitro antiplasmodial activity against the D6 (chloroquine-se...
متن کاملIsolation and Characterization of Leaf Extract of Derris Trifoliata
Derris trifoliata belongs to the family Fabaceae of the order Papilionoideae. D. trifoliata is used in local medicine in India as a stimulant, antispasmodic and counter-irritant, and against rheumatism, chronic paralysis and dysmenorrhoea. The bioactive principle present in the leaves of Derris trifoliata was isolated and characterized in the present study. The powdered leaves were repeatedly e...
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Two new prenylated flavonoids, named scariosin (1) and isorhynchospermin (2) were isolated from the leaves of paracalyx scariosa together with kaempferol, quercetin, kaempferol 3-O- rutinoside and rutin. The structures of (1) and (2) were characterized as 8-C- prenyl- taxifolin 7,3'-dimethylether and 6-C-prenylquercetin 7,4'-dimethylether by their chemical and spectra data, respectively.
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The plants in the genus Derris have proven to be a rich source of rotenoids, of which cytotoxic effect against cancer cells seem to be pronounced. However, their effect on angiogenesis playing a crucial role in both cancer growth and metastasis has been seldom investigated. This study aimed at investigating the effect of the eight rotenoids (1: -8: ) isolated from Derris trifoliata stems on thr...
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ژورنال
عنوان ژورنال: Molecules
سال: 2012
ISSN: 1420-3049
DOI: 10.3390/molecules17010657